The International Conference on Informatics and Semiotics in Organisations (ICISO) celebrates its 18th gathering. This conference is part of the series of international events devoted to latest research and application of informatics in organisations. Digitalisation, innovation, and transformation are the new drivers of development globally. As such, traditional business landscapes are rapidly evolving into new complex value creation webs across industries. With improved knowledge on information and communication technology, this evolution will continue to accelerate exponentially in the coming years. Organisational Semiotics (OS), with its profound theories, methods, and techniques provides the needed lens to investigate the complex nature of digitalisation, innovation, and transformation in the current business landscape.